Project Archive

D-Fines

The project focuses on the interaction between diet and sunlight exposure on vitamin D status and functional markers of bone health in premenopausal and postmenopausal Caucasian and Asian women living in Southern England at (51oN).

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Last updated: November 2008

Acid-Base and the Skeleton

This project focuses on two aspects: (1). Estimation of the intake of dietary acidity and alkalinity in the British population using the NDNS datasets; (2) the effects of the Atkins diet ,in comparison to a high fruit & vegetable weight loss diet, on markers of bone metabolism in men.

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Last updated: November 2008

Diet and Exercise on Bone

Our principal aim was to investigate longitudinal differences in bone quantity (BMC, BMD) and bone quality (quantitative ultrasound) between females participating in high impact loading exercise and normally active controls.

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Last updated: November 2008

Swiss Elderly

A cohort of 401 elderly ambulatory women (aged 80.4 y, BMI: 25.2 kg/m2) have been studied as part of the Swiss elderly studies. They are a sub-group of women who participated in the SEMOF (Swiss Evaluation of the Methods of Measurement of Osteoporotic Fracture Risk) study.

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Last updated: November 2008

Vitamin D and Bone in
Saudi Arabia

Few studies have been published examining BMD in healthy Saudi females. Ghannam et al (1999) measured bone mineral density (BMD) at the lumbar spine and the proximal femur in 321 Saudi females aged 10-50 years to establish normative data in Saudi females and to compare these data with their USA counterparts.

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Last updated: November 2008

Vitamin D and PBM in
Kuwait Females

Vitamin D deficiency was thought to be an epidemic in regions depleted from sun shine during winter months. Extensive evidence shows that this is not totally the case, as vitamin D deficiency is equally reported from regions which enjoy sun shine during the whole year. Interestingly, the Middle East has reported notable numbers of hypovitaminosis D among the general population, but more commonly among females (Lips, 2007).

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Last updated: November 2008

Trace Elements, Antioxidants and Bone

Exercise is reported to enhance the endogenous antioxidant defences. Repeated episodes of aerobic exercise has been reported to induce the expression of antioxidant enzymes. It is unknown whether these adaptive mechanisms differ with age. In animal models reduced glutathione (GSH) appears to be an important nonenzymatic antioxidant that plays a critical role in protection against oxidative stress induced by exercise.

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Last updated: November 2008

Protein Meta-Analysis and Bone

Dietary protein increases the production of the anabolic hormone, insulin like growth factor (IGF-1) and increases calcium absorption. IGF-1 increases bone mass by increasing osteoblast activity, and may increase mineralization of bone matrix. Therefore, protein deficiency may decrease bone strength and alter bone micro-architecture.

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Last updated: November 2008

Nutrition and Stress Fracture in
the Royal Marine Commandos

Further details to follow shortly.

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